Depo-Provera MDL Court Filings & CMOs

Pfizer, the manufacturer of the injectable contraceptive Depo-Provera, is currently facing lawsuits alleging a link between long-term use of the drug (and its generic equivalents) and the development of meningioma — tumors that form on the tissue lining the brain and spinal cord.

On February 7th, 2025, the Court decided to consolidate the federal court cases into a Multidistrict Litigation (MDL) in the Northern District of Florida under Judge Casey C. Rodgers.

Below are the currently available filings related to this ongoing litigation:

Depo-Provera MDL Case Filings

• 01/26/2026: Case Management Order No. 10 – Tenth CMC Summary, Expert Disclosure Deadlines & State Court Updates [PDF]
• 01/23/2026: Order – Supplemental Briefing Schedule for Pfizer’s Preemption Summary Judgment Motion [PDF]
• 01/06/2026: Pretrial Order No. 29 – Plaintiff Leadership Reappointment Process [PDF]
• 12/21/2025: Case Management Order No. 9 – Ninth CMC Summary, State Court Updates & 2026 Pilot Case Trial Setting [PDF]
• 12/02/2025: Third Amended Scheduling Order – Revised Deadlines for Pilot Cases [PDF]
• 11/25/2025: Case Management Order No. 8 – Eighth MDL CMC & Multi-Jurisdiction Updates [PDF]
• 11/21/2025: Pretrial Order No. 28 – 2026 Case Management Conference Schedule [PDF]
• 10/30/2025: Case Management Order No. 7 – Summary of October 24, 2025 Case Management Conference [PDF]
• 10/30/2025: Second Amended Scheduling Order – Initial Pilot Cases Discovery and Briefing Schedule [PDF]
• 10/29/2025: Stipulated Order Governing General Denial and Preliminary Statement of Defenses in Lieu of Individual Answers [PDF]
• 10/29/2025: Case Management Order No. 1 – Coordination Procedures and General Causation Schedule [PDF]
• 10/29/2025: Pretrial Order No. 1 – Stipulated Order Governing Confidentiality [PDF]
• 10/29/2025: Order Regarding Appointment of Data Administrator and Parties’ Use of MDL Centrality [PDF]
• 10/29/2025: Stipulated Order – Discontinuance of Claims Against Greenstone LLC and Viatris Inc. [PDF]
• 10/29/2025: Case Vetting Order – Identification of Deficiencies in Threshold Proof of Use and Injury Requirements [PDF]
• 10/29/2025: Stipulated Order Governing General Denial and Preliminary Statement of Defenses in Lieu of Answers [PDF]
• 10/24/2025: Administrative Order – Coordination of Depo-Provera Litigation [PDF]
• 10/03/2025: Case Management Order No. 6 – Sixth Case Management Conference Summary [PDF]
• 09/12/2025: Plaintiffs’ Response to Defendants’ Motion to Dismiss on Preemption Grounds [PDF]
• 09/11/2025: Pretrial Order No. 22A – Amendment Regarding Identification of Deficiencies in Threshold Proof of Use & Injury Requirements [PDF]
• 08/25/2025: Case Management Order No. 5 – Summary of Fifth CMC, Preemption Discovery Completion, Threshold Proof Updates & State Court Litigation Status [PDF]
• 07/16/2025: Pretrial Order No. 27 – Certification of Case Inventory Requirement for Plaintiffs’ Leadership Firms [PDF]
• 07/14/2025: Case Management Order No. 4 – Summary of Fourth CMC, Preemption Discovery, Questionnaire Compliance & MDL Centrality Updates [PDF]
• 07/07/2025: Pretrial Order No. 26 – General Denial and Preliminary Statement of Defenses in Lieu of Individual Answers [PDF]
• 07/01/2025: Pretrial Order No. 25 – Third-Party Litigation Funding Disclosure Requirement [PDF]
• 06/19/2025: Amended Scheduling Order – Revised Deadlines for Discovery, Preemption Motions, and General Causation Expert Disclosures [PDF]
• 06/11/2025: Case Management Order No. 3 – Updates from Third Case Management Conference, Discovery Status & Authorized Generic Defendant Review [PDF]
• 05/12/2025: Exhibit C – Standardized Complaint Template for Transferred Cases [PDF]
• 05/12/2025: Exhibit B – Standardized Direct-Filed Complaint Template [PDF]
• 05/12/2025: Exhibit A – Complaint Deficiency Review Process Protocol [PDF]
• 05/12/2025: Pretrial Order No. 23 – Identification of Deficiencies in Complaints [PDF]
• 05/06/2025: Proof of Use and Injury Review Process [PDF]
• 04/21/2025: Court Order – Authorized Generic Defendants Not Required to Sit for Depositions [PDF]
• 04/03/2025: Pretrial Order No. 21 – New Updates & Procedural Directives [PDF]
• 03/27/2025: Pretrial Order No. 20 – ESI Protocol: Greenstone & Viatris Document Production [PDF]
• 03/27/2025: Pretrial Order No. 19 – ESI Protocol for Prasco LLC Document Production [PDF]
• 03/16/2025: Pretrial Order No. 18 – Plaintiff and Defense Leadership Appointments [PDF]
• 03/15/2025: Pilot Case Scheduling Order – Discovery, Preemption, and Expert Deadlines [PDF]
• 03/15/2025: Case Management Order No. 2 – Summary of Second CMC, Rule 26 Report Issues & Pilot Case Updates [PDF]
• 03/14/2025: Plaintiff Proof of Use/Injury Questionnaire [PDF]
• 03/14/2025: Pretrial Order No. 17 – Threshold Proof of Use & Injury Requirements [PDF]
• 03/14/2025: Pretrial Order No. 16 – Deposition Protocol [PDF]
• 03/14/2025: Pretrial Order No. 15 – MDL Centrality Portal Activation [PDF]
• 03/14/2025: Pretrial Order No. 14 – Pfizer ESI Search & Validation Protocol [PDF]
• 03/14/2025: Pretrial Order No. 13 – Governing Production of Documents and ESI [PDF]
• 03/14/2025: Pretrial Order No. 12 – Stipulated Order on MDL Centrality Service [PDF]
• 03/14/2025: Pretrial Order No. 11 – Stipulated Order Governing Confidentiality [PDF]
• 03/13/2025: Pretrial Order No. 10 – Stipulated Order on Procedures for Direct Filing[PDF]
• 03/11/2025: Common Benefit Order No. 1 – Preliminary Procedures & Fee Guidelines [PDF]
• 03/11/2025: Pretrial Order No. 9 – Appointment of Common Benefit Special Master[PDF]
• 03/09/2025: Pretrial Order No. 8 – Plaintiff Leadership Presentations[PDF]
• 03/01/2025: Pretrial Order No. 7 – Appointment of Special Master[PDF]
• 03/01/2025: Pretrial Order No. 6 – Appointment of Data Administrator[PDF]
• 02/28/2025: Leadership Application Form – Plaintiff Counsel Information Sheet [PDF]
• 02/23/2025: Case Management Order No. 1 – Initial Case Management Conference & Pilot Case Selection [PDF]
• 02/28/2025: Pretrial Order No. 5 – Plaintiffs’ Leadership Applications & Interim Counsel Appointment
• 02/13/2025: Pretrial Order No. 4 – Docketing and Filing Procedures [PDF]
• 02/12/2025: Pretrial Order No. 3 – Notice of In-Person Attendance for Initial Case Management Conference [PDF]
• 02/11/2025: Pretrial Order No. 2 – Case Management Procedures and Pleading Extensions [PDF]
• 02/07/2025: Pretrial Order No. 1 – Assignment of Magistrate Judge Hope T. Cannon [PDF]
• 11/26/2024: Memorandum in Support of Motion for Transfer to Create MDL [PDF]

(More documents will be added as the case develops — bookmark this page to stay up to date.)

Depo-Provera Brain Tumor Lawsuit Information

To learn more about the connection between Depo-Provera and brain tumor risk, visit our Depo-Provera Brain Tumor Lawsuit information page.

For a free consultation with one of our Depo-Provera attorneys, call 202-792-7927.